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PEN-866 (formerly STA-12-8666)

Also known as: HDC SN-38

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Company Madrigal Pharmaceuticals Inc.
DescriptionHsp90-inhibitor drug conjugate (HDC) composed of an inhibitor of heat shock protein 90 (Hsp90) joined to SN-38 via a cleavable chemical linker
Molecular Target Heat shock protein 90 (Hsp90)
Mechanism of ActionHsp90 inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPreclinical
Standard IndicationSolid tumors
Indication DetailsTreat solid tumors
Regulatory Designation
PartnerTarveda Therapeutics Inc.

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