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Resolor, prucalopride (SHP555) (formerly SPD 555)

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Company Shire plc
DescriptionSerotonin (5-HT4) receptor agonist
Molecular Target Serotonin (5-HT4) receptor
Mechanism of ActionSerotonin (5-HT4) receptor agonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationConstipation
Indication DetailsTreat chronic constipation (CC); Treat non-cancer related opioid-induced constipation (OIC)
Regulatory Designation
PartnerJohnson & Johnson

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