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Sivelestat (ONO-5046)

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Company Ono Pharmaceutical Co. Ltd.
DescriptionSmall molecule inhibitor of neutrophil elastase
Molecular Target Neutrophil elastase (ELANE) (NE) (HLE)
Mechanism of ActionElastase inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationAcute lung injury
Indication DetailsTreat acute lung injury
Regulatory Designation

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