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SINE CRM1 antagonist

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Company Karyopharm Therapeutics Inc.
DescriptionOral selective inhibitor of nuclear export (SINE) protein exportin 1 (XPO1; CRM1) antagonist
Molecular Target Exportin 1 (XPO1) (CRM1)
Mechanism of Action 
Therapeutic Modality 
Latest Stage of DevelopmentPreclinical
Standard IndicationLupus
Indication DetailsTreat systemic lupus erythematosus (SLE)
Regulatory Designation

Partner


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