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doxepin (Silenor)

Also known as: SO-101

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Company Pernix Therapeutics Holdings Inc.
DescriptionLow-dose tricyclic doxepin
Molecular Target Histamine H1 receptor (HRH1) ; Histamine receptor
Mechanism of ActionHistamine H1 receptor antagonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationInsomnia
Indication DetailsTreat insomnia; Treat insomnia characterized by nocturnal awakenings and/or early morning awakenings; Treat insomnia in elderly patients; Treat primary chronic insomnia; Treat primary sleep maintenance insomnia; Treat transient insomnia
Regulatory Designation


CJ Group; Endo International plc; Procter & Gamble Co.

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