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Varubi, oral rolapitant (SCH 619734)

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Company Opko Health Inc.
DescriptionTachykinin receptor (TACR1; NK1R) antagonist
Molecular Target Tachykinin receptor (TACR1) (NK1R)
Mechanism of ActionTachykinin receptor (TACR1) antagonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationEmesis
Indication DetailsPrevent chemotherapy-induced nausea and vomiting (CINV); Treat post-operative nausea and vomiting (PONV)
Regulatory Designation
PartnerJiangsu Hengrui Medicine Co. Ltd.;
Tesaro Inc.

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