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entrectinib (formerly RXDX-101)

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Company Nerviano Medical Sciences s.r.l.
DescriptionOral c-ros proto-oncogene 1 receptor tyrosine kinase (ROS1), neurotrophic tyrosine kinase receptor 1 (TrkA; NTRK1), TrkB, TrkC and anaplastic lymphoma kinase (ALK) inhibitor
Molecular Target c-ros proto-oncogene 1 receptor tyrosine kinase (ROS1) ; Neurotrophic tyrosine kinase receptor 1 (TrkA) (NTRK1)
Mechanism of ActionKinase inhibitor; Anaplastic lymphoma kinase (ALK) inhibitor
Therapeutic ModalitySmall molecule

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Disease CategoryStandard IndicationIndication DetailsPartnersMilestonesLatest Stage of DevelopmentRegulatory Designation
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Total Number of DealsTotal Deal ValueTotal Upfront CashTotal Milestone Payments

2

$112.0M

$6.0M

$105.0M


 Deals Details
DateCompanies InvolvedDeal HeadlineTotal Deal ValueTotal Upfront CashTotal Milestone
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