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Nplate, Romiplate, romiplostim

Also known as: formerly AMG 531

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Company Amgen Inc.
DescriptionRecombinant fusion protein containing a pair of thrombopoietin (TPO) receptor-binding domains
Molecular Target Thrombopoietin (TPO) receptor (CD110) (Mpl)
Mechanism of ActionThrombopoietin (TPO) receptor (CD110) (Mpl) agonist
Therapeutic ModalityBiologic: Protein
Latest Stage of DevelopmentMarketed
Standard IndicationIdiopathic thrombocytopenic purpura (ITP)
Indication DetailsTreat chemotherapy-induced idiopathic thrombocytopenic purpura (ITP); Treat chronic idiopathic thrombocytopenic purpura (ITP); Treat idiopathic thrombocytopenic purpura (ITP)
Regulatory Designation

Switzerland - Orphan Drug (Treat chronic idiopathic thrombocytopenic purpura (ITP))

Partner

Kyowa Hakko Kirin Co. Ltd.; Kyowa Hakko Kirin Co. Ltd.


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