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Valcyte, Valixa, valganciclovir (R127, RG127)

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Company Roche
DescriptionProdrug formulation of ganciclovir, a guanine derivative nucleoside analog
Molecular Target Viral DNA polymerase
Mechanism of ActionViral polymerase inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationCytomegalovirus (CMV)
Indication DetailsPrevent cytomegalovirus (CMV) disease in kidney transplant patients; Prevent cytomegalovirus (CMV) disease in patients who have received a solid organ transplant; Prevent cytomegalovirus (CMV) disease in pediatric kidney and heart transplant patients; Treat cytomegalovirus (CMV) retinitis in HIV/AIDS patients
Regulatory Designation
PartnerMitsubishi Tanabe Pharma Corp.

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