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Relistor, methylnaltrexone (MNTX) (MOA-728, ONO-3849)

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Company Progenics Pharmaceuticals Inc.
DescriptionPeripheral mu opioid receptor (OPRM1; MOR) antagonist
Molecular Target Mu opioid receptor (OPRM1) (MOR)
Mechanism of ActionMu opioid receptor antagonist
Latest Stage of DevelopmentMarketed
IndicationConstipation
Partner

Ono Pharmaceutical Co. Ltd.; Salix Pharmaceuticals Inc.


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