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Also known as: formerly R115866, rambazole

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Company GlaxoSmithKline plc
DescriptionRetinoic acid metabolism blocking agent (RAMBA)
Molecular Target
Mechanism of Action 
Therapeutic Modality 
Latest Stage of DevelopmentPreclinical
Standard IndicationIchthyosis
Indication DetailsTreat autosomal recessive congenital ichthyosis; Treat congenital ichthyosis; Treat ichthyosis; Treat keratinopathic ichthyosis; Treat recessive X-linked ichthyosis
Regulatory Designation U.S. - Orphan Drug (Treat congenital ichthyosis);
EU - Orphan Drug (Treat autosomal recessive congenital ichthyosis);
EU - Orphan Drug (Treat keratinopathic ichthyosis);
EU - Orphan Drug (Treat recessive X-linked ichthyosis)

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