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Ralivia ER, Tramadol ER, Ultram, tramadol

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Company Valeant Pharmaceuticals International Inc.
DescriptionOnce-daily formulation of tramadol
Molecular Target Mu opioid receptor (MOR) (OPRM1) ; Monoamine transporters
Mechanism of ActionMonoamine reuptake inhibitor; Mu opioid receptor agonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationPain
Indication DetailsTreat low back pain; Treat moderate to moderately severe pain; Treat moderately severe pain; Treat pain
Regulatory Designation
PartnerJohnson & Johnson

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