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PSMA ADC

Also known as: Prostate vaccine

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Company Progenics Pharmaceuticals Inc.
DescriptionAntibody-drug conjugate (ADC) composed of a human mAb against prostate-specific membrane antigen (PSMA; FOLH1; GCPII) and monomethyl auristatin E (MMAE)
Molecular Target Prostate-specific membrane antigen (PSMA) (FOLH1) (GCPII)
Mechanism of ActionAntibody-drug conjugate
Therapeutic ModalityBiologic: Antibody-drug conjugate
Latest Stage of DevelopmentPhase II
Standard IndicationProstate cancer
Indication DetailsTreat metastatic castration-resistant prostate cancer (CRPC)
Regulatory Designation
Partner Seattle Genetics Inc.

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