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Hepsera, adefovir dipivoxil (GS 840)

Also known as: formerly Preveon

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Company Gilead Sciences Inc.
DescriptionSmall molecule nucleoside analog
Molecular Target Viral polymerase
Mechanism of ActionViral polymerase inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationHepatitis B virus (HBV)
Indication DetailsReduce risk of spreading hepatitis B to others; Treat chronic hepatitis B virus (HBV) infection; Treat chronic hepatitis B virus (HBV) infection in patients positive for hepatitis B e antigen (HBeAg); Treat hepatitis B virus (HBV) infection; Treat hepatitis B virus (HBV) infection in patients with compensated liver disease; Treat patients co-infected with HIV and lamivudine-resistant hepatitis B virus (HBV); Treat patients with HBeAg-negative chronic hepatitis B virus (precore mutant HBV infection)
Regulatory Designation
PartnerGlaxoSmithKline plc

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