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PLX7486

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Company Daiichi Sankyo Co. Ltd.
DescriptionSmall molecule inhibitor of colony-stimulating factor 1 receptor (CSF1R; C-FMS; CD115) and the receptor tyrosine kinases TrkA, TrkB, and TrkC
Molecular Target Neurotrophic tyrosine kinase receptor 1 (TrkA) (NTRK1) ; Colony-stimulating factor 1 receptor (CSF1R) (C-FMS) (CD115)
Mechanism of ActionColony-stimulating factor 1 receptor (CSF1R) inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase I
Standard IndicationSolid tumors
Indication DetailsTreat solid tumors
Regulatory Designation
Partner

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