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nitisinone oral suspension (Orfadin)

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Company Swedish Orphan Biovitrum AB
DescriptionOral suspension formulation of nitisinone, a synthetic reversible competitive inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD)
Molecular Target 4-hydroxyphenylpyruvate dioxygenase (HPPD)
Mechanism of Action4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentApproved
Standard Indication Metabolic (unspecified)
Indication DetailsTreat hereditary tyrosinemia type I
Regulatory Designation
PartnerSyngenta AG

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