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ornithine phenylacetate (oral OCR-002)

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Company Ocera Therapeutics Inc.
DescriptionOral formulation of an ammonia scavenger
Molecular Target
Mechanism of Action 
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase I
Standard IndicationLiver failure
Indication DetailsPrevent chronic hepatic encephalopathy; Prevent hepatic encephalopathy (HE); Treat acute liver failure; Treat hyperammonemia and resultant hepatic encephalopathy; Treat portal hypertension
Regulatory Designation U.S. - Fast Track (Treat hyperammonemia and resultant hepatic encephalopathy);
U.S. - Orphan Drug (Treat hyperammonemia and resultant hepatic encephalopathy);
EU - Orphan Drug (Treat acute liver failure)
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