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Oral neratinib (HKI-272, PB272)
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General Information
Company
Pfizer Inc.
Description
Oral inhibitor of HER1, HER2 and HER4 kinases
Molecular Target
Epidermal growth factor receptor 1 (EGFR1) (HER1) (ErbB1)
;
Epidermal growth factor receptor 2 (EGFR2) (HER2) (ErbB2) (neu)
Mechanism of Action
Epidermal growth factor (EGF) receptor 2 (HER2) (ErbB2) (neu) inhibitor; Epidermal growth factor (EGF) receptor 1 (HER1) (ErbB1) inhibitor
Product Summary: Number of Indications in each Phase of Development by Disease Category
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Product Details
Disease Category
Standard Indication
Indication Details
Partners
Milestones
Latest Stage of Development
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