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ONX 0801 (formerly BGC 945)

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Company BTG plc
DescriptionThymidylate synthetase (TYMS) inhibitor selective for cells expressing the folate receptor 1 (FOLR1; FR-alpha)
Molecular Target Thymidylate synthetase (TYMS)
Mechanism of ActionThymidylate synthase inhibitor
Therapeutic Modality 
Latest Stage of DevelopmentPhase I
Standard IndicationSolid tumors
Indication DetailsTreat advanced solid tumors
Regulatory Designation
PartnerAmgen Inc.

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