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Aloxi, Onicit, Paloxi, palonosetron

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Company Helsinn Healthcare S.A.
DescriptionSelective serotonin (5-HT3) receptor antagonist
Molecular Target Serotonin (5-HT3) receptor
Mechanism of ActionSerotonin (5-HT3) receptor antagonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationEmesis
Indication DetailsPrevent chemotherapy-induced nausea and vomiting (CINV); Prevent post-operative nausea and vomiting (PONV); Treat chemotherapy-induced nausea and vomiting (CINV)
Regulatory Designation


Eisai Co. Ltd.; Lee's Pharmaceutical Holdings Ltd.; Taiho Pharmaceutical Co. Ltd.

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