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briciclib (ON 013105)

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Company Onconova Therapeutics Inc.
DescriptionAnticancer drug that targets eukaryotic translation initiation factor 4E (elF4E) to drive cancer cells into apoptosis following mitotic arrest
Molecular Target Eukaryotic translation initiation factor 4E (eIF4E)
Mechanism of ActionCyclin D1 inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase I
Standard IndicationSolid tumors
Indication DetailsTreat advanced solid tumors
Regulatory Designation

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