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Fulyzaq, crofelemer (NP-303)

Also known as: CRO-ID (TRN-002)

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Company Napo Pharmaceuticals Inc.
DescriptionPurified proanthocyanidin oligomer extracted from the bark latex of the Amazonian tree Croton lechleri that acts as a partial antagonist of cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channel
Molecular Target Cystic fibrosis transmembrane conductance regulator (CFTR) ; Chloride channel
Mechanism of ActionCl channel antagonist; CFTR inhibitor
Latest Stage of DevelopmentApproved
IndicationDiarrhea (infectious)
Partner

Luye Pharma Group Ltd.; Salix Pharmaceuticals Inc.
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