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solitomab (AMG 110) (formerly MT110)

Also known as: formerly anti-Ep-CAM BiTE

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Company Amgen Inc.
DescriptionBispecific T cell engager (BiTE) antibody targeting the epithelial cell adhesion molecule (EpCAM) antigen and CD-3
Molecular Target Epithelial cell adhesion molecule (EpCAM) ; CD3
Mechanism of ActionBinds CD3; Binds epithelial cell adhesion molecule (EpCAM)
Therapeutic ModalityBiologic: Antibody
Latest Stage of DevelopmentPhase I
Standard IndicationSolid tumors
Indication DetailsTreat advanced solid tumors
Regulatory Designation


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