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tipelukast (MN-001) (formerly KCA-757)

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Company Kyorin Pharmaceutical Co. Ltd.
DescriptionLeukotriene receptor antagonist and inhibitor of phosphodiesterase-3 (PDE-3), PDE-4 and 5-lipoxygenase (ALOX5; 5-LO)
Molecular Target Phosphodiesterase-3 (PDE-3) ; 5-lipoxygenase (ALOX5) (5-LO)
Mechanism of Action5-lipoxygenase inhibitor; Phosphodiesterase-4 (PDE-4) inhibitor; Thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist
Therapeutic ModalitySmall molecule

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