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KarXT, LY246708 plus trospium chloride, xanomeline plus trospium chloride

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Company Karuna Pharmaceuticals Inc.
DescriptionMuscarinic acetylcholine receptor M1 (CHRM1; HM1) and CHRM4 (HM4) agonist plus a CHRM2 (HM2) and CHRM3 (HM3) antagonist
Molecular Target Muscarinic acetylcholine receptor M1 (CHRM1) (HM1) ; Muscarinic acetylcholine receptor M4 (CHRM4) (HM4)
Mechanism of Action 
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase I
Standard IndicationSchizophrenia
Indication DetailsTreat schizophrenia
Regulatory Designation
PartnerEli Lilly and Co.

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