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Company Lexicon Pharmaceuticals Inc.
DescriptionLocally-acting serotonin synthesis inhibitor
Molecular Target Tryptophan hydroxylase 1 (TPH1) (TPH) ; Tryptophan hydroxylase 2 (TPH2)
Mechanism of ActionTryptophan hydroxylase inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase II
Standard IndicationIrritable bowel syndrome
Indication DetailsTreat diarrhea-predominant irritable bowel syndrome (IBS-D); Treat irritable bowel syndrome (IBS)
Regulatory Designation U.S. - Fast Track (Treat diarrhea-predominant irritable bowel syndrome (IBS-D))

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