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Lotrel, amlodipine/benazepril

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Company Novartis AG
DescriptionCombination of amlodipine, a calcium (Ca) channel blocker, and benazepril, an angiotensin-converting enzyme (ACE) inhibitor
Molecular Target Angiotensin-converting enzyme (ACE) ; Calcium channel
Mechanism of ActionAngiotensin-converting enzyme (ACE) inhibitor; Calcium channel blocker
Therapeutic ModalitySmall molecule: Combination
Latest Stage of DevelopmentMarketed
Standard IndicationHypertension
Indication DetailsReduce cardiovascular morbidity and mortality in patients with high-risk hypertension
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