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KRN23, UX023

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Company Kyowa Hakko Kirin Co. Ltd.
DescriptionRecombinant human IgG1 mAb against fibroblast growth factor 23 (FGF23)
Molecular Target Fibroblast growth factor 23 (FGF23)
Mechanism of ActionAntibody
Therapeutic ModalityBiologic: Antibody
Latest Stage of DevelopmentPhase II
Standard Indication Musculoskeletal (unspecified)
Indication DetailsTreat tumor-induced osteomalacia (TIO); Treat X-linked hypophosphatemia (XLH)
Regulatory Designation

U.S. - Orphan Drug (Treat X-linked hypophosphatemia (XLH));
EU - Orphan Drug (Treat X-linked hypophosphatemia (XLH))


Ultragenyx Pharmaceutical Inc.

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