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volanesorsen (ISIS 304801) (formerly ISIS-APOCIIIRx)

Also known as: APOC-III antisense inhibitor

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Company Isis Pharmaceuticals Inc.
DescriptionApolipoprotein C-III (APOCIII; APOC3) antisense inhibitor
Molecular Target Apolipoprotein C-III (APOCIII) (APOC3)
Mechanism of ActionAntisense therapy
Therapeutic ModalityNucleic acid: Linear RNA: Antisense
Latest Stage of DevelopmentPhase III
Standard IndicationHypertriglyceridemia
Indication DetailsTreat familial chylomicronemia syndrome; Treat hypertriglyceridemia
Regulatory Designation U.S. - Orphan Drug (Treat familial chylomicronemia syndrome);
EU - Orphan Drug (Treat familial chylomicronemia syndrome)
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