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Irtra, Irbesartan/trichloromethiazide (S-474474)

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Company Shionogi & Co. Ltd.
DescriptionCombination of a small molecule angiotensin II receptor antagonist and a thiazidal antihypertensive diuretic
Molecular Target Angiotensin II type 1 (AT1) receptor (AGTR1)
Mechanism of ActionAngiotensin II type 1 (AT1) receptor antagonist
Therapeutic ModalitySmall molecule: Combination
Latest Stage of DevelopmentMarketed
Standard IndicationHypertension
Indication DetailsTreat hypertension
Regulatory Designation Japan - Standard Review (Treat hypertension)
Partner Sanofi

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