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Duragesic, Ionsys, fentanyl iontophoretic transdermal system (SyB P-1501)

Also known as: fentanyl (formerly E-trans)

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Company Johnson & Johnson
DescriptionNeedle-free, patient-controlled, preprogrammed delivery system of fentanyl, a mu opioid receptor (MOR; OPRM1) agonist
Molecular Target Mu opioid receptor (MOR) (OPRM1)
Mechanism of ActionMu opioid receptor agonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationPain
Indication DetailsManage acute postoperative pain during hospitalization; Manage acute postoperative pain in adults requiring opioid analgesia during hospitalization; Manage acute, moderate to severe postoperative pain; Pain management following major surgery; Treat chronic pain; Treat persistent, moderate to severe chronic pain
Regulatory Designation
PartnerSymBio Pharmaceuticals Ltd.;
The Medicines Co.

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