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HRAS and survivin UsiRNA formulated in a single DiLA2 lipid-based delivery vehicle

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Company Marina Biotech Inc.
DescriptionDuplex short interfering RNAs (siRNAs) modified with unlocked nucleobase analogs (UNA) formulated in a DiLA2 liposome formulation targeting HRAS and survivin
Molecular Target v-Ha-ras Harvey rat sarcoma viral oncogene homolog (HRAS) ; Survivin (BIRC5)
Mechanism of ActionGene silencing
Therapeutic ModalityNucleic acid: Linear RNA: siRNA
Latest Stage of DevelopmentPreclinical
Standard IndicationBladder cancer
Indication DetailsTreat bladder cancer
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