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Homologous Recombination Deficiency (HRD) assay, myChoice HRD

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Company Myriad Genetics Inc.
DescriptionAssay that detects when a tumor has lost the ability to repair double-stranded DNA breaks
Molecular Target Breast cancer 1 early onset (BRCA1) ; Breast cancer 2 early onset (BRCA2)
Mechanism of ActionDiagnostic
Therapeutic ModalityDiagnostics
Latest Stage of DevelopmentMarketed
Standard IndicationCancer, Diagnostic
Indication DetailsDetect loss of DNA repair function in tumors; Predict pathological response following neoadjuvant platinum-based therapy in triple-negative or BRCA1/2 mutation-associated breast cancer
Regulatory Designation
PartnerTesaro Inc.

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