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Heplisav (V270)

Also known as: HBV vaccine (HBV-ISS vaccine)

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Company Dynavax Technologies Corp.
DescriptionHepatitis B surface antigen (HBsAg) given with immunostimulatory DNA sequences that target toll-like receptor 9 (TLR9) as adjuvant
Molecular Target Toll-like receptor 9 (TLR9)
Mechanism of ActionVaccine
Therapeutic ModalityPreventive vaccine
Latest Stage of DevelopmentPhase III
Standard IndicationHepatitis B virus (HBV)
Indication DetailsPrevent HBV infection; Prevent HBV infection caused by all known subtypes in adults ages 18-70 years and in patients with chronic kidney disease (CKD); Prevent HBV infection for patients with end-stage renal failure; Prevent HBV infection in chronic kidney disease (CKD) patients; Prevent HBV infection in patients on dialysis
Regulatory Designation

U.S. - Undisclosed Review (Prevent HBV infection caused by all known subtypes in adults ages 18-70 years and in patients with chronic kidney disease (CKD))

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