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Company Baxter International Inc.
DescriptionGlucose analog conjugated to an alkylating agent
Molecular Target DNA
Mechanism of ActionAlkylating agent
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase III
Standard IndicationPancreatic cancer
Indication DetailsSecond-line treatment of relapsed or refractory pancreatic cancer; Treat advanced pancreatic cancer as first-line therapy; Treat pancreatic cancer; Treat refractory metastatic pancreatic cancer; Treat unresectable locally advanced or metastatic pancreatic adenocarcinoma
Regulatory Designation

U.S. - Fast Track (Treat unresectable locally advanced or metastatic pancreatic adenocarcinoma);
U.S. - Orphan Drug (Treat pancreatic cancer);
U.S. - Special Protocol Assessment (Treat pancreatic cancer);
EU - Orphan Drug (Treat pancreatic cancer)


Eleison Pharmaceuticals Inc.; MediBIC Group; Threshold Pharmaceuticals Inc.

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