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Gliadel, Gliadel Wafer, carmustine implant (NPC-08)

Also known as: polifeprosan 20 with carmustine implant

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Company Eisai Co. Ltd.
DescriptionBiodegradable polymer implant containing carmustine
Molecular Target DNA
Mechanism of ActionBreaks/crosslinks DNA
Therapeutic ModalityMedical Devices: Drug/device combination
Latest Stage of DevelopmentMarketed
Standard IndicationBrain cancer
Indication DetailsAdjunct to surgery in patients with recurrent glioblastoma multiforme (GBM); First-line treatment for malignant glioma; Initial surgery for high-grade malignant glioma; Initial surgery for malignant glioma; Treat brain cancer; Treat glioblastoma brain tumor; Treat high-grade malignant glioma; Treat malignant glioblastoma multiforme (GBM); Treat malignant glioma; Treat metastatic brain cancer; Treat newly diagnosed malignant glioma; Treat patients with malignant glioma undergoing primary surgical resection; Treat primary glioblastoma multiforme (GBM); Treat recurrent glioblastoma multiforme (GBM); Treat recurrent glioma
Regulatory Designation


Arbor Pharmaceuticals Inc.; BioPro Pharmaceutical Inc.; Nobelpharma Co. Ltd.

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