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bercaplermin, Gemesis (GEM 21S)

Also known as: Beta tricalcium phosphate plus PDGF

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Company Wright Medical Group N.V.
DescriptionCombination of recombinant human platelet derived growth factor BB (PDGFBB) and a resorbable synthetic bone matrix
Molecular Target Platelet derived growth factor receptor A (PDGFRA) (PDGFR2) (CD140A) ; Platelet derived growth factor receptor B (PDGFRB) (PDGFR1) (CD140B)
Mechanism of ActionPlatelet derived growth factor receptor A (PDGFRA) agonist; Platelet derived growth factor receptor B (PDGFRB) agonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationPeriodontitis
Indication DetailsTreat bone defects from periodontal disease
Regulatory Designation
PartnerDaiichi Sankyo Co. Ltd.

 Product Details
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Total Number of DealsTotal Deal ValueTotal Upfront CashTotal Milestone Payments

1

$395.3M

$42.5M

$190.0M


 Deals Details
DateCompanies InvolvedDeal HeadlineTotal Deal ValueTotal Upfront CashTotal Milestone

03/11/2013

$395.3M

$42.5M

$190.0M

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