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Foretinib (1363089) (GSK1363089) (formerly XL880)

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Company Exelixis Inc.
DescriptionInhibitor of c-MET and VEGFR-2
Molecular Target Vascular endothelial growth factor (VEGF) receptor 2 (VEGFR-2) (KDR/Flk-1) ; c-Met receptor tyrosine kinase
Mechanism of ActionVascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) kinase inhibitor; Binds Met receptor
Therapeutic ModalitySmall molecule

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Disease CategoryStandard IndicationIndication DetailsPartnersMilestonesLatest Stage of DevelopmentRegulatory Designation
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