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Firdapse, amifampridine

Also known as: 3,4-DAP, 3,4-diaminopyridine (formerly Zenas)

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Collapse Summary General Information
Company BioMarin Pharmaceutical Inc.
DescriptionPotassium channel blocker
Molecular Target Potassium channel
Mechanism of ActionK channel blocker
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard Indication Autoimmune (unspecified)
Indication DetailsTreat Lambert-Eaton myasthenic syndrome (LEMS)
Regulatory Designation

U.S. - Breakthrough Therapy (Treat Lambert-Eaton myasthenic syndrome (LEMS));
U.S. - Orphan Drug (Treat Lambert-Eaton myasthenic syndrome (LEMS));
EU - Orphan Drug (Treat Lambert-Eaton myasthenic syndrome (LEMS));
Switzerland - Orphan Drug (Treat Lambert-Eaton myasthenic syndrome (LEMS))

Partner

Catalyst Pharmaceutical Partners Inc.; Jazz Pharmaceuticals plc


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