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FG-2216, YM311

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Company FibroGen Inc.
DescriptionSmall molecule inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH)
Molecular Target Hypoxia-inducible factor prolyl hydroxylase (HIF-PH) (EGLN)
Mechanism of ActionHypoxia-inducible factor prolyl hydroxylase inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase II
Standard IndicationAnemia
Indication DetailsTreat anemia; Treat anemia in chronic kidney disease (CKD) patients who are recombinant erythropoietin (EPO) naïve; Treat renal anemia
Regulatory Designation
PartnerAstellas Pharma Inc.

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