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RG6061 (formerly EZN-2968, SPC2968)

Also known as: HIF-1 alpha antagonist

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Company Roche
DescriptionLocked nucleic acid-based hypoxia-inducible factor 1 alpha (HIF1-alpha) antagonist
Molecular Target Hypoxia-inducible factor 1 (HIF1)
Mechanism of ActionHypoxia-inducible factor 1 alpha (HIF-1 alpha) antagonist
Therapeutic ModalityNucleic acid: Linear RNA
Latest Stage of DevelopmentPhase I
Standard IndicationSolid tumors
Indication DetailsTreat advanced solid tumors or lymphoma; Treat solid tumors
Regulatory Designation

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