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Dafiro, Exforge, amlodipine/valsartan

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Company Novartis AG
DescriptionCombination of the calcium channel blocker amlodipine and the angiotensin receptor blocker valsartan
Molecular Target Angiotensin II type 1 (AT1) receptor (AGTR1) ; Calcium channel
Mechanism of ActionAngiotensin II type 1 (AT1) receptor antagonist; Calcium channel blocker
Therapeutic ModalitySmall molecule: Combination
Latest Stage of DevelopmentMarketed
Standard IndicationHypertension
Indication DetailsTreat hypertension; Treat hypertension as a first-line therapy
Regulatory Designation


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