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Ryanodex, dantrolene (EP-4104)

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Company Eagle Pharmaceuticals Inc.
DescriptionLyophilized formulation of dantrolene, a sodium muscle relaxant
Molecular Target Ryanodine receptor 1 (RyR1)
Mechanism of Action 
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard Indication Metabolic (unspecified)
Indication DetailsTreat exertional heat stroke (EHS); Treat malignant hyperthermia
Regulatory Designation U.S. - Fast Track (Treat exertional heat stroke (EHS));
U.S. - Orphan Drug (Treat malignant hyperthermia);
U.S. - Priority Review (Treat malignant hyperthermia)

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