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Emend, Ivemend, Proemend, fosaprepitant dimeglumine, fosaprepitant meglumine (MK-0517, ONO-7847)

Also known as: Emend For Injection

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Company Merck & Co. Inc.
DescriptionInjectable formulation of the selective neurokinin 1 (NK1) receptor antagonist
Molecular Target Neurokinin 1 (NK1) substance P receptor (TACR1)
Mechanism of ActionNeurokinin-1 (NK-1) (Substance P) receptor antagonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationEmesis
Indication DetailsPrevent chemotherapy-induced nausea and vomiting (CINV); Prevent chemotherapy-induced nausea and vomiting (CINV) in cancer patients ages 6 months-17 years; Treat digestive symptoms resulting from the administration of antineoplastic agents.
Regulatory Designation
Partner Ono Pharmaceutical Co. Ltd.

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