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Elelyso, Uplyso, alfataliglicerase, taliglucerase alfa (formerly prGCD)

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Company Protalix BioTherapeutics Inc.
DescriptionPlant cell-expressed recombinant form of human glucocerebrosidase (GCase)
Molecular Target Glucocerebrosidase (GBA) (GCase)
Mechanism of ActionEnzyme replacement therapy
Therapeutic ModalityBiologic: Enzyme
Latest Stage of DevelopmentMarketed
Standard IndicationGaucher's disease
Indication DetailsTreat Gaucher's disease; Treat Type I Gaucher's disease; Treat Type I Gaucher's disease in pediatric patients
Regulatory Designation U.S. - Expanded Access (Treat Gaucher's disease);
U.S. - Fast Track (Treat Gaucher's disease);
U.S. - Orphan Drug (Treat Gaucher's disease);
U.S. - Special Protocol Assessment (Treat Gaucher's disease);
EU - Orphan Drug (Treat Type I Gaucher's disease);
Australia - Orphan Drug (Treat Gaucher's disease);
Canada - Standard Review (Treat Gaucher's disease)
Partner Pfizer Inc.

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