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morphine sulfate extended-release (Arymo ER) (formerly Egalet-001)

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Company Egalet Corp.
DescriptionOral extended-release formulation of morphine sulfate that uses Egalet's Guardian Technology abuse-deterrent technology
Molecular Target Mu opioid receptor (MOR) (OPRM1)
Mechanism of ActionMu opioid receptor agonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentRegistration
Standard IndicationPain
Indication DetailsTreat moderate to severe chronic pain; Treat pain severe enough to require daily, around-the-clock opioid treatment and for which alternative treatments are inadequate
Regulatory Designation U.S. - Fast Track (Treat moderate to severe chronic pain)
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