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Dulanermin (Apo2L/TRAIL) (AMG 951, RG3639)

Also known as: rhApo2L/TRAIL

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Collapse Summary General Information
Company Genentech Inc.
DescriptionAgonist of death receptors DR4 and DR5
Molecular Target Tumor necrosis factor (TNF) receptor superfamily member 10a (TNFRSF10A) (DR4) (TRAILR1) (CD261) ; Tumor necrosis factor (TNF) receptor superfamily member 10b (TNFRSF10B) (DR5) (TRAILR2) (CD262)
Mechanism of ActionTRAIL-R1 agonist; TRAIL-R2 agonist
Therapeutic ModalityBiologic: Protein

 Product Details
Disease CategoryStandard IndicationIndication DetailsPartnersMilestonesLatest Stage of DevelopmentRegulatory Designation
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