Dulanermin (Apo2L/TRAIL) (AMG 951, RG3639)

Company	Genentech Inc.
Description	Agonist of death receptors DR4 and DR5
Molecular Target	Tumor necrosis factor (TNF) receptor superfamily member 10a (TNFRSF10A) (DR4) (TRAILR1) (CD261) ; Tumor necrosis factor (TNF) receptor superfamily member 10b (TNFRSF10B) (DR5) (TRAILR2) (CD262)
Mechanism of Action	TRAIL-R1 agonist; TRAIL-R2 agonist

Product Details

Disease Category	Standard Indication	Indication Details	Partners	Milestones	Latest Stage of Development