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Cyclurad (NRX-101)

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Company NeuroRx Inc.
DescriptionFixed-dose combination of D-cycloserine, a glycine site NMDA receptor antagonist, and lurasidone, a small molecule antagonist of the 5-HT2A receptor
Molecular Target NMDA receptor ; Serotonin (5-HT2A) receptor
Mechanism of Action 
Therapeutic Modality 
Latest Stage of DevelopmentPhase II/III
Standard IndicationDepression
Indication DetailsTreat acute suicidal ideation and behavior; Treat depression and suicidality in patients with bipolar disorder
Regulatory Designation

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