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NormoCort, levoketoconazole (COR-003)

Also known as: COR003

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Company Strongbridge Biopharma plc
Description2S,4R-enantiomer of ketoconazole, an inhibitor of cytochrome P450 family 11 subfamily B polypeptide 1 (CYP11B1), CYP17A1 and CYP21A2
Molecular Target Cytochrome P450 family 11 subfamily B polypeptide 1 (CYP11B1) ; Cytochrome P450 family 17 subfamily A polypeptide 1 (CYP17A1)
Mechanism of ActionCytochrome P450 inhibitor
Therapeutic Modality 
Latest Stage of DevelopmentPhase III
Standard IndicationCushing's disease
Indication DetailsTreat Cushing's syndrome; Treat endogenous Cushing's syndrome
Regulatory Designation U.S. - Orphan Drug (Treat Cushing's syndrome);
EU - Orphan Drug (Treat Cushing's syndrome)

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