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Contrave, Mysimba, naltrexone SR/bupropion SR (NB32)

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Company Orexigen Therapeutics Inc.
DescriptionFixed-dose combination of naltrexone sustained release (SR) and bupropion SR
Molecular Target Mu opioid receptor (MOR) (OPRM1)
Mechanism of ActionMu opioid receptor antagonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationObesity
Indication DetailsTreat obesity
Regulatory Designation U.S. - Special Protocol Assessment (Treat obesity);
U.S. - Undisclosed Review (Treat obesity);
EU - Standard Review (Treat obesity)
PartnerConsilient Health Ltd.;
Kwang Dong Pharmaceutical Co. Ltd.;
Valeant Pharmaceuticals International Inc.

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